Our results show that somatic neuromuscularendplates contain a full complement of all active zone proteins.
1
These observations show that SCs participate actively in the remodeling of neuromuscularsynapses following nerve injury by their guidance of axonal reinnervation.
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We have investigated the possible role of synapsin I, a nerve terminal-specific protein, in the maturation of neuromuscularsynapses in Xenopus cell cultures.
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This review summarizes recent findings about the role of neurotrophic factors in modulating synaptic efficacy of neuromuscularsynapses, both in an activity-dependent and -independent fashion.
Uso de neuromuscular junction em inglês
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The protein also localized to the postsynaptic region of the neuromuscularjunction.
2
This mutation leads to aberrant synaptic transmission at the neuromuscularjunction.
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Electron microscopy of the neuromuscularjunction was normal in both patients.
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This has important implications for the understanding of the molecular mechanisms of neuromuscularjunction formation.
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MG is an immune-mediated disorder caused by molecular mimicry and autoantibodies against the neuromuscularjunction.
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Fatigue of peripheral nervous system components, including the contractile apparatus and the neuromuscularjunction, has been well studied.
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We also tested whether P2X signaling is required for myogenesis or synaptic communication at the zebrafish neuromuscularjunction.
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The neuromuscularjunction (NMJ) is a highly developed synapse linking motor neuron activity with muscle contraction.
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Clinical features and stimulation single-fiber electromyogram were consistent with a neuromuscularjunction transmission disorder, likely Lambert-Eaton myasthenic syndrome.
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We now present functional data from studies on the larval neuromuscularjunction that reveal abnormal synaptic architecture and physiology.
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Here we demonstrate that Cln7 is required for the normal growth of synapses at the Drosophila larval neuromuscularjunction.
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A disorder of the neuromuscularjunction was suspected and he was subsequently demonstrated to have a congenital myasthenic syndrome.
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Furthermore, compound 13 was as active as tacrine in reversing the blockade induced by tubocurarine at rat neuromuscularjunction.
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The effects of high doses of nicotinic alkaloids are biphasic, and eventual persistent depolarization of nAChRs at the neuromuscularjunction occurs.
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We begin by describing the expression of proteins necessary for optimal neuromuscularjunction function that results in the muscle cell action potential.
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Studies on the neuromuscularjunction and central inhibitory synapses suggest that clustering of neurotransmitter receptors requires its interaction with a cytoplasmic protein.